I did'nt and have'nt had a single problem with the installation, and I replaced a BM6 Intel BX based board with the Epox. Here's what I did.
First I removed my sound card, nic, and modem from Device Manager. I also removed the associated drivers. I shut down the computer and manually removed them from my computer. restarted in Safe Mode to make sure they had been removed, and removed any items still showing. Then I booted back into Windows, and in Device Manager I removed my Hard Drive/IDE drive Controllers, and also removed the USB devices (any thing that said Intel). I then shut down the computer to remove the old Motherboard and install the new one.
Installed the new Motherboard and let Windows ask for/look for the new controllers, ect., and added components 1 by 1 through a series of shut downs, re-starts.