1. Don't stare at it all day. Take a break.
2. Avoid most LED monitors. Some are good, but many are harsh cool white LEDs, and/or neutral white with plenty of spectral gaps (there is no way to fix this after the fact). It sucks, but I'm sticking with old crap for a little while longer, until better LED backlighting, and/or
true LED monitors (OLED, w/ no backlight), get cheap and plentiful. Don't be so quick to toss out those old 1280x1024 IPS monitors for the new 1080P hotness
.
3. Avoid Lattitudes, and mainstream Inspirons, IMO. Most have been coming with very poor quality displays, lately. Be careful when choosing a display. Glossy = bad. Like hot women with all that make-up on, it looks good as a quick distraction, but it's not what you want to see day in and day out. IMO, B&M notebooks are not even worth looking at, because of that.
4. Increase your DPI! Don't make everything fuzzy by using a non-native res. Instead, make things bigger in your native res.
4A. Apple is way ahead of Microsoft on this.
5. You can't tell who uses slow PWM and who doesn't, unfortunately, but PWM can be discerned, and have negative effects, up to a few kHz. You don't "see" it, because it's not detected around the center of your vision, but rather, your periphery. CCFL PWM dimming resulted in a gradual bright/dim cycle, much like incandescent bulbs. Not so for LEDs. The annoying bit is that it can cause fatigue, but be fast enough to not be consciously perceived.
6. Prescription glasses are made with a focal point. Your glasses can't change angle, like contacts can, so you are not looking out of the ideal area when looking just a few feet away. I'm near-sighted, and not too bad, so I
can get away with not wearing mine in front of a computer, but that's not an option for many, and probably won't be for me in 10-20 years (though, I expect to have corrective surgery by then, and only need minor correction via glasses
). You can get a pair made for up-close use, and even get added anti-UV, anti-glare, and blue reduction, for dealing with fluorescent lighting and computer monitors.
And...that's all I got.