If you use RAID0 I suggest you keep the drives well defragged if you want to see an increase in performance.
RAID0 will not increase drive seek performance. It increases STR by quite a lot no doubt about that, but often it's the seek performance that will dictate your overall performance, not STR, so even though you have huge gains in STR you won't see much gain in performance.
Unfortunately a lot of hard drive benchmarks put alot more weight on STR than most regular usage will, so RAID0 looks more attractive from most benchmarks than it really is.
That coupled with everything that Patrick already raised about reliability concerns would make me think long and hard about RAID0.
It is possible you have some applications that will be heavily STR limited in which case you will see big gains by a RAID0, but usually the STR increases just won't help you that much.
If you want to increase seek performance, go for a high speed SCSI drive, 10k RPM or 15k RPM will give you much better seek performance than a pair of striped ATA drives, which will win on STR depends on the drives Areal density, but if all the drives are new likely the ATA RAID will have some edge in STR, though likely not enough to offset the Seek Performance gain from SCSI.
All in all I'd take a single SCSI drive over an ATA RAID for Workstation performance in most cases, but it is somewhat application domain dependant.