The Simpson Family
Homer Jay Simpson, father
Marjorie Bouvier Simpson, mother
Bartholomew Jo-Jo Simpson, son
Lisa Marie Simpson, daughter
Margaret Simpson, baby daughter
Extended Family:
Abraham J. Simpson, Homer's father
Mona J. Simpson, Homer's mother
Jacqueline Bouvier, Marge's mother
Unnamed, Marge's father, seen only in flashbacks
Selma Bouvier Terwilliger Hutz McClure, one of Marge's sisters, a twin to Patty
Patty Bouvier, the other of Marge's sisters, a twin to Selma
Herbert Powell, Homer's half-brother
Abbie, Homer's English half-sister
Pets:
Snowball, cat (deceased)
Snowball II, longlived cat (deceased, see Snowball V)
Snowball III, cat (deceased)
Coltrane, cat (deceased)
Snowball V, cat, a.k.a. Snowball II
Santa's Little Helper, greyhound
Laddie, border collie, super-dog, male version of Lassie, owned by Bart
Princess, pony, owned by Lisa
Duncan/Furious D., racehorse, owned by Homer
Stampy, elephant, owned by Bart
Jub-Jub, iguana, owned by Selma, inherited from Aunt Gladys Bouvier
Chirpy Boy & Bart Junior, Bolivian tree lizards, owned by Bart
Mojo, helper monkey, owned by Homer
Pinchy, lobster, owned by Homer (deceased, consumed by Homer)
Unnamed, screamapillar, an endangered lepidoptera
Variously named, 25 true-bred greyhounds, offspring of Santa's Little Helper and "Tex" O'Hara's She's The Fastest
Variously named, a few greyhound/poodle mixed-breeds, offspring of Santa's Little Helper and Dr. Hibbert's poodle Rosa Barks
Other Families
The Flanders Family
Nedward (Ned), father, owner of Leftorium
Maude, mother (deceased)
Rod, son
Todd, son
Grandma Flanders (senile and decrepit many years earlier; likely deceased)
Pets:
Mr. Bunny, rabbit, (deceased)
Related:
Unnamed, Ned's beatnik parents (seen in flashbacks)
Unnamed, Ned's sister
Unnamed, Ned's multi-continental extended family
The Van Houten Family
Kirk, former Southern Cracker factory manager, now unemployed or variously so
Luann, ex-wife
Milhouse, son, Bart's best friend
Nana, grandmother
The Nahasapeemapetilon Family
Apu, Kwik-E-Mart convenience store owner and proprietor
Manjula, wife
Their octupletss (with assumed stage names):
Poonam (Animal)
Sashi (Dazzle)
Pria (Punchline)
Uma (The Baron)
Anoop (the rest)
Sandeep (the rest)
Nabendu (the rest)
Gheet (the rest)
Sanjay, Apu's brother
Pahusacheta, Sanjay's daughter
Mrs. Nahasapeemapetilon, Apu's mother
The Wiggum Family
Clancy, incompetent chief of police
Sarah, wife
Ralph, mentally challenged son
The Hibbert Family
Dr. Julius, Simpson family doctor
Bernice, wife, recovering alcoholic
unnamed children, including at least one son and one daughter
Pets:
Rosa Barks, poodle
The Lovejoy Family
Timothy, reverend of First Church of Springfield
Helen, wife, town gossip
Jessica, daughter, trouble-maker
The Spuckler (or Delroy) Family
Cletus, slack-jawed yokel
Brandine, wife (and sister?)
children: Tiffany, Heather, Cody, Dylan, Dermot, Jordan, Taylor, Brittany, Wesley, Rumor, Scout, Cassidy, Zoe, Clo, Max, Hunter, Kendall, Caitlin, Noah, Sascha, Morgan, Kyra, Ian, Lauren, Q-bert, Phail, Condoleezza Marie, Rubella Scabies
Ma, Cletus's mother
DiaBetty, cousin
Cousin Merl, cousin
Curly Sue, indeterminate relative
Pets:
Geech, smellhound
The Carstairs Family
Admiral Carstairs, society patron
Lady Carstairs, wife, society matron
Unnamed, daughter, debutante
Springfield Nuclear Powerplant
Charles Montgomery Burns, owner
Waylon Smithers, executive assistant, sycophant/lickspittle/toady
Lenny Leonard
Carl Carlson
Charlie
Zutroy
Tibor
Jack Marley (retired)
Mindy Simmons (fired)
Frank Grimes, a.k.a. Grimey (deceased)
Karl, former executive assistant of Homer, (dismissed)
Pops Freshenmeyer
Blinky, three-eyed fish, sometime mascot, one of many so mutated due to power plant's radiation
Related:
Aristotle Amadopolis, owner, Shelbyville Nuclear Power Plant
Mrs. Burns, Montgomery's 122 year old mother
Larry Burns, Montgomery's illegitimate son
Ernest K. Smithers, father and professional predecessor to Waylon Smithers (deceased)
Springfield Elementary School
Administration
Seymour Skinner, principal, a.k.a. Armin Tanzarian, lives with his mother Agnes
Superintendent Chalmers, sometimes date of Agnes Skinner
Leopold, Chalmers's assistant
Teachers
Ms. Edna Krabappel, fourth-grade teacher, former fiancée to Seymour Skinner (Bart's teacher)
Mrs. Audrey McConnell, third grade teacher
Miss Elizabeth Hoover, second-grade teacher (Lisa's teacher)
Mr. Dewey Largo, music teacher
Mr. Schindler, art teacher
Mr. Glascock, teacher (retired)
Mrs. Blumenstein, teacher, debate team coach
Mr. Sikorsky, shop teacher
Mrs. Cummerdale, gym teacher
Mrs. Pummelhorse, gym teacher
Mr. Bergstrom, substitute teacher
Staff
Willie, groundskeeper, all-around hero,scottish,
Doris, lunchlady & nurse
Dr. J. Loren Pryor, school psychiatrist
Coach Fortner, coach, alcoholic
Otto Mann, bus driver, stoner, guitarist, once engaged to be married, death metal fan, holds record for over 10 crashes without a single fatality
Students
Nelson Muntz, bully, known for his scornful laugh
Jimbo Jones, bully, with wool cap
Dolph, bully, with long bangs
Kearney, bully, bald, divorced father of one
Francine, bully, tormentor of Lisa
Martin Prince, nerd extraordinaire
Database, nerd, with curly hair
Ham, nerd, with little sprout of hair
E-Mail, nerd
Report Card, nerd
Cosine, nerd
Wendell, nervous student, pale skin, vomits frequently
Louis
Richard
Janie
Sherrie and Terrie, purple-haired twins, their father has a top-level position at the power plant
Allison Taylor, Lisa's fellow-overachieving classmate
Alexis Whitney, Lisa's super-hip classmate
Rex, highly dramatic stage actor
Tommy, breathtaking boy in Bart's class
Üter, German exchange student (once thought deceased, merely absent)
School Pets
Superdude, gerbil, (deceased)
Nibbles, hamster
Mrs. Nibbles, hamster, 'wife' to Nibbles, mother to and consumer of various offspring
Lumpy, snake
Stinky & Wrinkles, goldfish (Deceased due to Yo-Yo incident)
Unnamed, turtles
Government, Police, Law
Mary Bailey, state governor
Mr. Atkins, state comptroller
"Diamond" Joe Quimby, mayor
Big Tom, mayoral bodyguard
Ernie, mayoral bodyguard
Chief Clancy Wiggum, chief of police
Lou, police sergeant
Eddie, police officer
Various police dogs:
Bobo
Scraps
Sniffy
Laddie
Judge Multon, veteran judge
Judge Roy Snyder, veteran judge, known for lenient punishment
Judge Constance Harm, newer judge, known for vindictive punishment (a Judge Judy parody)
Judge Muntz, grandfather to Nelson
Related:
Unnamed, mayor's wife (a Jacqueline Kennedy Onassis parody)
Unnamed, mayor's numerous mistresses, including Miss Springfield
Freddy Quimby, mayor's nephew, troublemaking playboy
Clovis Quimby, mayor's nephew (brother?)
Roxie, mayor's secretary
Amy, police sergeant Lou's ex-wife
Criminal Element
Snake, a recidivist crook (hold-ups, break-ins, muggings, etc.)
Don Vittorio DiMaggio, godfather
Anthony "Fat Tony" D'Amico, mob boss
Joey, mob henchmen
"Legs", mob henchmen
Louie, mob henchmen
Johnny "Tight-Lips," mob henchmen
Frankie "the Squealer," mob henchmen/informant
Business Figures
Unnamed, corporate attorney, nasally and pasty-faced lawyer with blue hair
Lionel Hutz, incompetent lawyer and one time real estate broker
Gil, incompetent lawyer, as well as incompetent salesman of real estate, cars, shoes, computers (a parody of Jack Lemmon's character in the movie Glengarry Glen Ross)
Colonel Antoine "Tex" O'Hara, oil tycoon, former owner Springfield Isotopes, former owner She's The Fastest greyhound, owner traveling carnival, humidor maker
Howard K. Duff VIII, owner Duff Beer, owner Springfield Isotopes
Barry "Duff Man" Duffman, product promoter (current holder of the title, others were Larry & Sid)
Jack Larson, president Laramie Cigarettes
Lindsay Neagle, entrepreneur, sexual predator
Cookie Kwan, successful realtor on the westside
Unnamed comic book guy, owner Android's Dungeon & Baseball Card Shop
Unnamed "Yes" guy, restauranteur, waiter and host (a Frank Nelson parody) Sound Clip
Akira, restauranteur behind the Happy Sumo
Captain Horratio McAllister, restauranteur behind the the Frying Dutchman and charter boat operator
Herman, veteran, owner Herman's Military Antiques
Prof. John Frink, scientist, inventor, entrepreneur
Local Media Personalities
Television
Krusty the Klown, Herschel Schmoikel Krustovsky, entertainer
Rabbi Hyman Krustovsky, rabbi and Krusty's formerly estranged father
Sophie, Krusty's daughter
Lois Pennycandy, Krusty's personal assistant
Sideshow Bob, Robert Underdunk Terwilliger, former sidekick of Krusty, repeat attempted-murderer
Cecil Terwilleger, Bob's jealous younger brother
Sideshow Mel, Melvin Van Horn, Bob's humble but eloquent replacement
Sideshow Raheem
Mr. Teeny, trained monkey on Krusty's show, former minister of tourism of Brazil
Corporal Punishment, background player on Krusty's show
Gina Ballerina, another Krusty regular
Kent Brockman, local anchorman for KBBL-TV (Channel 6), real name Kenny Brockelstein
Arnie Pye, "Pye in the Sky," disgruntled Channel 6 traffic helicopter reporter
Bumblebee Man, Spanish language television host on KMEX-TV (Channel Ocho), real name likely Pedro
Emma, Bumblebee Man's ex-wife
Unnamed actor, the hard-nosed television character MacGarnicle in the show of the same name
Roger Meyers, Jr., chairman of "Itchy and Scratchy International"
Roger Meyers, Sr., founder of "Itchy and Scratchy International"
Chester J. Lampwick, creator of cartoon character "Itchy" and cartoon violence
June Bellamy, the voice of cartoon characters Itchy & Scratchy (a June Foray reference)
Movies
Troy McClure, washed-up movie star
MacArthur Parker, McClure's agent
Rainier Wolfcastle, a.k.a. McBain, famous action hero
Maria, wife
Greta, daughter
Buck McCoy, aging Spaghetti Western cowboy legend
Señor Spielbergo, director, Steven Spielberg's non-union Mexican equivalent
Radio
Various radio stations include:
KBBL-FM, typical FM music format
KBBL-AM, "K-Babble", all talk radio
KOMA-AM, "Coma", restful easy listening
KFSL-FM, "Fossil", classic rock
KUDD-AM, country/western
KJAZZ-AM, mostly jazz
WOMB, "warm and safe radio..."
Bill and Marty, radio team on KBBL-FM
"Jerry Rude and the Bathroom Bunch" with shock-jock Jerry Rude (a Howard Stern parody)
"Moleman in the Morning" with Hans Moleman, on KJAZZ
"Gabbin' About God" on KBBL-AM with Rev. Timothy Lovejoy, Rabbi Hyman Krustovsky, and Msgr. Kenneth Daly
Birch Barlow, host of conservative call-in show on KBBL-AM (a Rush Limbaugh parody)
Dr. Marvin Monroe, call-in psychiatrist on KBBL-AM (once thought deceased, merely very ill)
Music
Bleeding Gums Murphy, jazz musician (deceased)
Lurleen Lumpkin, country western singer/songwriter
Be Sharps, Grammy winning barbershop quartet
Party Posse, boyband
Rachel Jordan/Kovenant, Christian rock
Larry Davis Band, frequent live performers at local functions
Sports & Other Personalities
Drederick Tatum, professional heavy-weight boxer
Lucius Sweet, professional boxing promoter
Rasputin the Friendly Russian, formerly the Mad Russian, professional wrestler
Dr. Hillbilly, professional wrestler
Iron Yuppie, professional wrestler
Professor Werner von Brawn, professional wrestler
Clay Babcock, two-time Fast Car champion
Ronnie Beck, three-time soapbox derby champion
Stan "The Boy" Taylor, football player, Springfield Atoms
Flash Bailey, baseball player, Springfield Isotopes
Captain Lance Murdock, daredevil
Moe's Tavern
Moe Syzlak, owner and proprieter
Barney Gumble, former boozehound
Sam, barfly, with green hat and glasses
Larry, barfly, taller & balding
Hugh Jass
Joey Jo-Jo Junior Shabadoo
Medical Practices
Dr. Julius Hibbert, doctor (originally a Bill Cosby parody)
Dr. Nick Riviera, doctor, shifty in nature
Dr. Wolfe, dentist
Dr. Marvin Monroe, psychiatrist (once thought deceased, merely very ill)
Dr. J. Loren Pryor, psychiatrist
Dr. Foster, psychiatrist
Unnamed, cosmetic surgeon