What kind of computer will you be running on? If its a windows machine with IIS, then ASP would be a much better choice, both for the platform and for hooking into an mdb file.
If you know php will work on your system, then you would need something like:
$db = 'path to your database';
$conn = new COM('ADODB.Connection');
// Two ways to connect. Choose one.
$conn->Open("Provider=Microsoft.Jet.OLEDB.4.0; Data Source=$db");
//$conn->Open("DRIVER={Microsoft Access Driver (*.mdb)}; DBQ=$db");
That will connect you to the DB file. You can then use sql statements to query the table you want, make new tables, and write data to the tables. The above will only work if your running on a windows platform. If your not running on windows, im not sure how to make the connection.