I've lived this thing - from first landing ALT in Aught'77 to the last one today.
Birth to Tomb.
If we really want to get serious about exploration of space, either close beyond LEO, or out to the fringes of our
solar group we need something large - not a can of spam for sitting in an outhouse for years at a time in diapers.
Logistics dictates that you need supplies to be re-stocked, and waste disposal at frequent intervals.
Do you want to spend 30 - 60 days in such confined quarters, and conusume minimal quantities of proteoid capsules
and recycled water filtered for by-products, and save every piece of trash and assorted waste particulates?
We took on a program to modulary configure the ISS, and that's been shown that would be a do-able program.
The single biggest barrier is the initial gravity well that we have to lift above to some quasi-stable orbit
in order to emplace some form of structural assembly position, where modular components can
be positioned, collected, and assembled into some intercoupled integrated system, like the ISS is designed
except make it assemble into a large spacious homogenous structure that can safely accomodate a large crew
as many as 20 individuals in a big robust enviromental container with subsystem walls, bulkheads, presssure
hatches and portals that permit the crew freedom to move around, and a large enough vessel to carry
supplies, methods for conversion/disposal, and scientific equipment to explore any event that manifests intrest.
We already would have to stage payloads along the way to Mars if we just want to tweak out for a look.
It's at least 6 months out one way, so there you have to place 3 supply vessles in pre-determined rendezvous
places, first pair as supply vaults 60 days out and another 60 days apart, with the third having a lander
if any attempt is made to go to the surface.
If this is done, the lander has to also ground launch, return to mother, dock and transfer.
The way back can take another 9 months, so coming back after the first 30 days will need re-supply
as some of the lander/supplier materials will be nearing exhaustion, so 30 days after maybe 2 or 3 weeks
on target, with a couple or 3 days on the surface, they need to exchange supplies before takin on
the longer 60 days between stations - they have to make transfer 4 more times.
Each re-supply vault has to launch and be parked before the launch on the way out,
the outermost
return module can be launched at the same window to their predetermined rondezvous points,
and the remaining 4 can go out incrementally for their specific locations, and be met when needed
but you can't miss the target or it's over, terminally.
It would take 7 supply heavy lifter, and one man-lifter to start the ball rolling - spam grand tour.
But . . . if 7 missions were flown with cargo, and personel, to assemble an interlocking
mechanical construction
which modulary composed a larger vessel which incorporated the 27.5' Dia. x 154' tanks like the Shuttle,
or 33' x 138' like Saturn S-1C for external tanks, and grouped the tanks into nestling cores
placing a ring of 6 around 1 central tank into a cluster, and add the interlocking modules at the 'front'
leaving the thrusters in place in the rear.
Residual propellants, if suitable, can be used to supply water, breathable oxygen atmoshpere,
and to supply electrical power with fuel cells to augment deployed solar arrays that can
overlay the
entire vehicle. We have already thrown away 135 external tanks of this size, they are already spaced
so insert, capture, and collect to assemble a vast self contained structure - the mating elements
are already there, it needs the interface modular components, and becomes an expandable item.
Throw that out on a mission where it can rondezvous with deeper staged re-supply vehicles in
LaGrange Points, and make some serious push outward, and after a year outbound bring it back.
meanwhile in the 2 year travel interval, continue building the next expansion modular phase that will
attach on orbit and change crews, and make the next deep exploration to possibily a Jovian LaGrange
and deposit that second phase modular collection there, and go back and get another.
7 tanks to a cluster - we've thrown out 135. That could have made almost 20 LaGrange elements.
An alternate configuration would be a wheel of 6 tanks with spoke clusters forming tripods
on either side of the wheel, with modules forming the wheel to spoke interfaces and the end hub sprockets.
That would make LaGrange Station Orbits functional, while the other module cluster is the traveler.