Originally posted by: Wreckage
From the benchmarks I have seen dual GTX295s would be the fastest setup. (unless you count something crazy like the guy who has 23 of them).
Not only will it crush any game (including GTAIV) but just think of what you can do with CUDA..... PhysX, Folding, Video editing and transcoding, etc. etc.
Your own personal super computer.
Plus you will be more than ready for OpenCL...
http://www.nvidia.com/object/cuda_opencl.html
"As part of the OpenCL presentation NVIDIA featured the world's first OpenCL GPU demonstration"