While I have an extensive tech background, it was years ago when PC133 was the standard. Now things have changed so dramatically that I consider myself new to the scene again, and I'm learning from the ground up.
I run a DFI nF4 Ultra-D (since I am not that big of a gamer, I do not mind not having SLI) and it's pretty easy to set up. Yes, there are a ton of options, and it can be confusing, but the initial setup is a breeze, and the board is feature-rich. When you want to OC and mess around, you'll have all the option you want and need to max out performance.
Good luck!