First let me explain that I'm not an "expert" on this matter. I can just relay what I have seen done in various avionics applications.
A lot depends on the construction of your heatsink. I've seen some sinks that are walled-in on two opposing sides with openings only on the remaining two, and the top, which limits ingress/egress. If you have that type, you would definitely not want all 3 fans blowing in the same direction. That would give you large amounts of air being pushed into a confined space(or pulled from) with no exit, basically limiting movement. Remember, you are trying to remove heat.
If your sink is open on all four sides, with extremely narrow spacing between the fins, then you would have to determine whether the original fan, moves more or less air than the pair of add-ons. I'm going to assume that your add-ons move more, and then I would suggest(only my opinion) that you have both of the add-ons blow out, and the top mounted fan blow towards the sink.
If your sink is the type that has a smaller quantity of fins with very large air spaces allowing unrestricted air flow, then either, all in or all out would probably be equivalent. Although I would lean towards all out.
I can't quote you an exact physical law, but, it would be similar to using multiple case fans where it appears it is better to have more air being pushed out than in. Ideally, you would want equal in/out.
Also remember, this is all a moot point if your case is not ventilated properly to begin with. You could have an industrial sized squirrel cage fan inside your closed case moving large CFM, but If you don't have a source of "cooler" air entering the case, you're just exchanging 'warm' air coming out of your fans, for 'warm' air being pushed into the sink.
In extreme conditions, liquid cooling(Coolinol) is top choice, but there are the inherent problems associated with having liquid and electricity confined in close proximity.
Again, I must repeat that the above is not based on some science I have learned/understand, but on assembling electronics that were designed by knowledgable(hopefully

)individuals.
Now if I could only figure out how to use the Javascript buttons at the top of the message window
