Refs are refs (it is what it is). SEA needs to remember to ignore the calls and play--use it as a motivator. You cannot control the refs/bad calls, but the key is remaining focused.
That said there have been some calls, poor or not (I think they are poor), that have been significant as they changed the score or continued IND drives: the Safety instead of a TD on the punt block (looked like a TD), the PI call on Tate (did Tate even tough him? Ref was from the other side of the field), Baldwin being tackled before he got the ball and no PI called, and the PI call against Browner (questionable).
Oh well, that is how it goes. Typical of a road game--so it is up to Seattle to raise their level of play. You cannot blame the refs.