Yesterday I tested the hybrid CM10 install with a 32GB class 4 SanDisk card- I saw no noticeable difference in anything directly compared to a 32GB class 10 SanDisk card. I'm guessing this only makes a difference on an SD-only install.
I bit the bullet and upgraded to CM10.1 installed internally (thanks to uallas5 for all the info). All I can say is- everything is now flawless. Even though I didn't mind it, there's now not even a slight rotation delay. Even my magnetic cover now sleeps and wakes the device when open/closed. (With hybrid CM10 it would only wake when opened.)
An absolute must IMO is to flash xboxexpert's Tablet UI mod after gaaps setup. I didn't care much for the weirdly centered on screen buttons and space-wasting top notifications bar, but the Tablet UI fixed this.
I guess any issues with 10.1 have been figured out because install took less than five minutes, no trouble at all.
I did a backup of stock first, but I don't miss it at all. Good riddance, CM10.1 is a far superior experience.