Some people just don't like having a massive heatsink impeding access to everything or some have cases they simply won't fit in. There's a variety of cases that will take a 280mm radiator but not one of the massive tower coolers.
Definitely an important point. I can imagine folks picking a case for building a system based on the aesthetics primarily, then wishing this or that feature or lack of feature supported their emerging needs as the building goes through a "discovery" process.
Answering Elkido122, I think there is an EKWB Predator 280. There is most certainly a 360 model, but looking at Maximum PC's recent 5960X "silent" system built with EKWB parts, you're left with a limited set of places for HDD and SSD storage, like the back-side of the motherboard pan accessible from the right side-panel. Me? I need an optical disk and some hot-swap bays. And I want some front-panel USB3 ports and eSATA ports.
As opposed to the PRedator line, you can get EKWB kits with various part specs that include radiators as desired.
For the record, I'll give the rundown on "accessibility problems" I face with my own Skylake system in a Stacker 830 with a TR LG Macho. The fins are designed as I said to leave the mobo area forward of the processor latch completely unobstructed, more or less as you choose to install a 120 or 140 mm pusher fan. I can reach the top x1 PCIE slot to install a card -- a bit tedious. Slightly less tedious for connecting SATA cables to a PCIe controller in that slot. For me, I have to pull off a Lexan motherboard duct to get at anything, but all the cables are laid and hardware installed so that it just pops on and pops off: I have to slide it carefully over the Macho fins, but that's no problem either. There is only one item which is really difficult to access: the 40mm Noctua intake fan at the I/O plate, made inaccessible by the TR accessory accordion duct of the Macho. In order to get at that fan, I must first remove all 9 motherboard mounting screws (with a magnetic screwdriver, certainly), and I have to slide the motherboard an inch or two forward so that the accordion duct can be removed or pushed aside to access the fan-plate.. Then, again with the magnetic Phillips, I must remove two screws on that plate installed in the plastic shroud of my Sabertooth's I/O plate and VRMs, and remove the Noctua from the plate.
If the 40mm fan is being replaced, then we go through the same process once more in reverse.
You can ask yourself "what kind of access?" and "How often this access?" I'm fine with the Macho. I was just thinking today that I could look again at the Predator 280, the Swiftech H240 X2 and similar items. I could look at some kits. I could look at some quick-release fittings. I could fret over it considerably. I just don't know at this point, but the old Stacker 830 is completely ready to rock-and-roll in the water.
You can check the OS forum to see what I've been through lately to feel that I've reached the top of Everest or K2 without water-cooling. All I want to do at this state of affairs is game and game and game, or fool around with my other software. For most things, the processor never heats up beyond 45C. That shouldn't change much, if I crank it back up to 4.7 Ghz after troubleshooting my Build 1703 difficulties. I will still match the performance of either the EKWB or H240 X2 by themselves each with a completely virgin retail-box shrink-wrapped processor. Mine was re-lidded with CLU for a 12C improvement in temperatures.