False. It is usually possible to replace a motherboard in a Dell with a non-Dell replacement. Dell almost always uses standardized motherboards except in its slim chassis, including the BTX motherboard being discussed (which was a standard, BTW, just not a widely adopted or popular one).Dell's use OEM motherboards that are often not exactly to standard formfactors. It is usually not possible to replace a motherboard in a Dell except with a Dell replacement.