- Mar 22, 2006
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So we're doing alcohol synthesis now, and studying Grignard reagents (MgX). I know the criteria for regular grignard reactions - backside attacks of carbonyls, blah blah. What I'm fuzzy on is the (usually unwanted) side reactions of Grignard reagents, such as with water, protons, double bonds, etc.
My book has the mechanism for Grignard + water reactions, but it goes on to say that Grignards will be protonated by OH, NH, SH, and acetylene, and Grignards will also attack double bonds - C=O, C=N, C...N, S=O, N=O. What I don't understand is exactly how the Grignard reacts with these last two. Does the proton attach directly onto the Grignard - HMgX? What about the R group of the Grignard? And I have no idea how it works with the double bonds...
EDIT: got help from a friend, don't think I need the answer anymore.
My book has the mechanism for Grignard + water reactions, but it goes on to say that Grignards will be protonated by OH, NH, SH, and acetylene, and Grignards will also attack double bonds - C=O, C=N, C...N, S=O, N=O. What I don't understand is exactly how the Grignard reacts with these last two. Does the proton attach directly onto the Grignard - HMgX? What about the R group of the Grignard? And I have no idea how it works with the double bonds...
EDIT: got help from a friend, don't think I need the answer anymore.
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