There's no good substitute for doing your own research. If you don't know what an "MCP-1" or a "RAID-o-a blah blah blah" is, you are far more likely to toast that unlocked 2500+ than overclock it successfully. However, in the interest of boosting AMD's sales, I'll tell you why I prefer the MSI:
1) The ATX connector is in a sane location in "front" of the board, as opposed to the back, where you have to drape twenty wires across the CPU heatsink and connect them between the back ports and the HSF.
2) The IDE connectors are at the mid-level, where they should be, not lower. Helps with reaching top bays on tower cases without needing to use out-of-spec IDE cables
3) Passive northbridge cooling - no cheezy, whiny sleeve-bearing fan that'll die in 1-2 years.
4) SPDIF out. SPDIF transmits audio in digital format - either an encoded 5.1 surround stream from a DVD, or stereo sound from games, etc. Not like using onboard audio is advisable if you're overclocking. If you're spending the effort to boost your CPU speed, don't waste these processor cycles on software audio - buy a decent sound card.