Best resolution? 2560x1440 144-165hz+ with G Sync
If the game isn't too demanding you can max it out and enjoy high framerates. If it is demanding, you should be able to still get 60fps max settings unless the game is horribly optimized or has BS max settings like infinite draw distance or "Hyper" settings that no one can notice.
Lots of room to tweak to your preferences here too. Turn down a few settings in demanding games if you like high framerate. Or crank up super sampling AA to get a super sharp picture on less demanding games where you value IQ over framerate.