[*]cas 2-2-2-6 would be considered tight timings
[*]1:1 (synch) & 5:4 (asynch) would be considered FSB (front side bus) / memory ratio. AMD should stay 1:1, and Intel can do either one without diminishing returns. As an example the benefit of an asynch on Intel boards is that if you have PC3200 (200MHz) but want to run 250MHz to overclock the cpu, you'd use a 5:4 setting since your memory will most likely not run @ 250MHz.