It could be wrong or dead electric connections to activate the pixels. Or it could be also a problem in the polarising film.
   A LCD screen has a backlight, and that light is polarised thru a filter. Another substrate, parallel, is the "programable" polarizer. The "programmable" polarizer is capable to either polarize the light in a direction rotated 90* or to let it pass (or polarize in the same direction as the other filter). When the direction of polarisation is rotated 90*, the screen blacketh ( 

 ). If not, the light can go thru, and a lighted spot appears.
   The "programmable" polarizer is controlled with voltages (electric fields, like in condensers). The presence of the field changes the polarisation plane, compared to the absence of the electric field. Those "cells" (which are sub-pixels on a color screen) keep their information thanks to some "static RAM" cells, so no refresh is needed.
   Well, when one or more of the transistors are defective, the (sub)pixel can be either dead (black) or stuck (white).