I haven't experienced any printer problems on USB but on my main system, using an Asus CUSL2-C board, I used to sometimes not have my USB mouse power up at start up and had to unplug/replug, sometimes 2 or 3 times, to get it working. Also, have an Intel web cam plugged in to the USB port through a USB hub built into my ADI monitor. At fairly frequent intervals, happened about 4 times today over the course of 3 hours, the cam quits working. Requires doing the unplug/plug routine to get it working. Using Win2K and am not sure if it is a hardware problem related to the motherboard, OS problem, combination of both or what. Not a big problem but a bit frustrating. Just flashed a new BIOS into the board last night and the not starting up the mouse problem seems maybe to have gone away. Only time will tell.