Junk Food 'Addiction' May Be Real

[Gonad the Barbarian]

http://www.businessweek.com/lifestyle/content/healthday/637430.html

Obese people often say they'd like to eat less but feel almost powerless to stop indulging, and now new research suggests that explanation might be all too true.

The theory stems from a study in rats. When researchers gave the rats unlimited access to a calorie-laden diet of bacon, pound cake, candy bars and other junk food, the rats quickly gained lots of weight. As they plumped up, eating became such a compulsion that they kept chowing down even when they knew they would receive an unpleasant electric shock to their foot if they did so.

Meanwhile, rats fed the human equivalent of a well-balanced, healthy diet -- and given only limited access to the junk food -- didn't gain much weight and knew enough to stop eating when they received the cue that a foot shock was imminent.

Even more startling, the researchers report, is that when they took away the junk food from the obese rats and replaced it with healthier chow, the obese rats went on something of a hunger strike. For two weeks, they refused to eat hardly anything at all.

"They went into voluntary starvation," said study author Paul Kenny, an associate professor at Scripps Research Institute in Jupiter, Fla.

So what might this say about human behavior?

Researchers aren't certain if the results apply to people struggling with their weight. But they say it's possible that a diet heavy in highly rewarding foods -- quite literally, sausages, cheesecake and other highly processed foods -- might cause changes in the brain's reward system for satiety.

When that goes awry, the result is not only that people gain weight, but that they feel compelled to seek out more and more junk food.

The findings were published online March 28 in Nature Neuroscience.

When researchers looked at the obese animals' brains, they noted there were declines in the dopamine D2 receptor that previous research has implicated in addiction to cocaine and heroine.

"A hallmark of drug addiction is that it leads to changes in how the brain's reward system works," Kenny said. "Addiction is a loaded term, but in this case, there is evidence of addiction-like adaptations."

When researchers artificially suppressed the receptor using a virus in the brains of other rats, those rats starting eating junk food compulsively.

"What we think is happening is that, as you become obese over a period of time, the D2 receptors go down, which plays a major role in becoming a compulsive eater," Kenny said, noting there are almost certainly other factors at play as well.

There also could be something in the accumulated fat itself that alters the brain's reward threshold, setting up a "vicious cycle" of overeating yet not feeling satisfied, said Pietro Cottone, an assistant professor in the Laboratory of Addictive Disorders at Boston University School of Medicine.

"The only way to return to normality is probably dieting for a long period of time to lose the body weight and not eating junk food," Cottone said.

This isn't the first study to find commonalities between the brain's reaction to cupcakes and illicit drugs. An earlier study by Cottone and his colleagues suggested that weaning rats off a high-calorie diet might lead to similar, though not identical, effects in the brain as withdrawing from drugs and alcohol.

In that study, researchers gave rats a regular diet for five days and then switched them to a chocolate-flavored food that was high in sugar. When deprived of the sugary food, they showed signs of anxiety and their brains acted as if they were withdrawing from alcohol or drugs. The study was published last November in the Proceedings of the National Academy of Sciences.

In the current study, the rats were raised on healthy foods, but their preferences quickly shifted when offered junk food. Throughout the day, they snacked and nibbled, rapidly bulking up. And the more they gained, the more they ate.

"That poses a huge conundrum for humans," Kenny said. "It shows you how powerful this behavior can become."

Dr. Julio Licinio, director of the John Curtin School of Medicine Research at the Australian National University, called the study answers "one of the many missing pieces in the puzzle of obesity and addiction."

"Now that it is clear that areas of the brain involved in addiction and also involved in obesity, the next question is: Why do those areas become dysregulated in some people, but not in others?" Licinio asked. "And importantly, why do some people who have a biological tendency towards addiction go to drugs, while others go to alcohol, and others go to food?"

 

[rcpratt]

Oh good, more excuses for people to be fat.

 

[brikis98]

Oh good, more excuses for people to be fat.

Or... perhaps yet anoter sign that the type of food you eat makes a huge difference.

 

[Whisper]

Or... perhaps yet anoter sign that the type of food you eat makes a huge difference.

Agreed. Personally, more than an "excuse for being fat" per se (although I'm sure that's how it'll strike some people), I see the study as being an area of promising research for developing more effective eating intervention programs. Then again, I tend to be highly optimistic and idealistic.

 

[Kipper]

I'd be very, very careful about generalizing too much about human behavior from a rat study...

 

[McWatt]

Hey, I incorporate bacon into both cutting and building. Don't besmirch its name. Just eat in moderation.

 

[The Sauce]

I learned a long time ago that there was no such thing as one cookie, or one piece of chocolate or slice of pizza. I treat it like an addiction. No sugar, no processed foods, no fast foods... Just on special occasions, but not in everyday life.

 

[skace]

In this age of excess, learning to hate food is your smartest move.

 

[fleshconsumed]

Oh good, more excuses for people to be fat.

The more people are aware of the dangers of junk food, the more likely they are to avoid those foods.

I'm just glad there are finally some studies such as this one or one about HFCS from last week validating what many of us already knew. Maybe the rest of the people will heed the advice and cut down on the junk food.

 

[Red Dawn]

In this age of excess, learning to hate food is your smartest move.

No, learning to hate being excessive would be smart, being smart about what you eat is the way to go.

 

[ZOOYUKA]

Personally, I think it has more to do with laziness. It is much easier to buy prepackaged food and go through the drive thru than cooking a meal for yourself or making the effort to find a better alternative.

 

[SociallyChallenged]

I'd be very, very careful about generalizing too much about human behavior from a rat study...

Agreed. Food addiction is already known as a human psychological disorder. However, junk food addiction might be a stretch until further research is done on humans. I doubt research in America would have trouble finding people to participate in that kind of study 😛 Either way, it's interesting to ponder.

 

[darkxshade]

This might explain why I still crave junk food even when I'm not hungry. Fortunately, I have some semblance of self control since I'm health conscious now. If I weren't[in that I didn't exercise and cared about my health], I can see myself gorging on junk food because I did used to do that. I would buy a bag of chips and once I open it, I just eat the whole damn bag. I still fall victim of my old habits on occasion but what has helped is that I have absolutely no junkfood at home.