Don't know how small, but as just an exercise in imagination:
it seems likely a nano machine could pump liquid or gas through a nanotube creating a jet. Maybe the pump could be powered by chemical reactions with the medium it's submerged in, or perhaps from bioelectric energy, such as is created when neurons fire.
Could be invisibly tiny enough to sit in the alveoli to aid respiration in people suffering breating problems, jetting oxygen into the bloodstream and Co2 out. Or maybe floating inside your blood vessels to do something or other.