It seems most of you don't understand the annuity option (which isn't surprising).
The annuity automatically increases 4% each year for inflation. Also, the lump sum is the cash value at the point (which is usually about half) and then you're taxed nearly another 50%. It is very unlikely you are going to make more than the initial winning. If it is 600 million, you're getting around 150 million in lump sump, while that is a large amount, it is a lot less than the 10+ million you get for the next 30 years.
Also, the annuity IS transferable upon death. It is part of your estate.
I also believe (but powerball.com is blocked at work), upon taking the annuity, the state puts the cash value in a investment account they choose and you get any gains, while having the base value guaranteed.
Personally, I'd only take lump sum if the value was over say 300 million, and even then the first thing I'd do is hire and accountant / money manager and discuss it with them.
Oh, and this is based on the US multi state lotteries. If you're in another country, my advice might be different.