The one little difference that you might see is that running 2 processes simultaneously with anything other than a large cache CPU (ie., Xeon), will mean that the time/WU on each will be a bit longer than if you ran only 1 process on the dual. That's because the cache isn't big enough to hold the program, although 3.03 was created to swap ~200K-sized pieces of the program in and out of 256K-size caches. Thus running 2 means some fighting over the use of the slower RAM.
Still, I'll take me a dually anything, any day! 😀