Yes, I get tired of it. Like others have mentioned, I used to get into the tweaking/fixing thing, but now I just want it to work. I'm tired of fiddling for 3 hours to get 5 more FPS in Unreal Tournament. I'm tired of messing around with BIOS settings to stop my computer from locking up in 3D games. I'm tired of playing the driver of the week game with nVidia and now ATI. I am fully capable of tweaking and troubleshooting my own machines, I just get annoyed doing it lately.
When I'm working on someone else's machine, I have NO patience for things not working. I just want it to work, and get it done and over with quickly.