Hondas are great cars. So are Toyotas, but Hondas are more fun to drive (while a Toyota is generally more comfortable) and Hondas usually have a slight edge in fuel economy. With good care, 200,000 miles should be easy, and 300,000 is definitely not out of the question, especially for an Accord.
My current ride is a ?92 Civic LX with almost 151,000 miles on it. It runs like new, but it uses a quart or so of oil between changes.
Dino oil in an Accord is definitely good enough when it's changed every 3000 miles. I'm another person who would never drive 10,000 miles on any oil, synthetic or not, so I would be "wasting" my money. My '87 automatic (carb'd LX, dino oiled) had 247,000 on it when I accidentally ditched it and f'd the suspension.

I swear it was actually running stronger than it's rated 98 horses. The completely original transmission was still doing great, too. It had it's fluid changed (partial drain and refill with Honda brand fluid) as recommended every 15,000 miles or so. It's as easy as an oil change because Honda used a drain plug and no filter. It took 2.7 quarts, about $12.
If you want durability, go for an Accord over a Civic, IMHO. I did have an 89 Civic that had 192,000 miles on it (running like new) when it met it's unfortunate end in a morning rush hour pile up, but I still think the Accord has more potential, for a couple of reasons. It's more expensive, and so is not quite as subject to cost cutting to keep the base price under a certain point. As such, you'll have better luck finding one with fastidious maintenance by a dealer or other Honda specialist, who knows which aftermarket replacement parts to avoid using. Also, the larger engine in the Accord is torquier, so it is generally run at lower revs, and doesn?t need to be ?flogged? as often to merge, etc. (as most people know, if all other factors are equal, an engine will last longer at lower revs).
To the dude who is having problems with brakes and exhaust, I?m sure you?re not taking it somewhere that uses Honda parts, or the brake pads would be silent, and the exhaust would last 8 years, even in salty Minnesota. Cheap parts should never go on a car that you want to keep for years. Another common aftermarket part failure on Hondas is the drive shafts. The originals last 100,000 miles, but cheap, ?lowest quote? parts don?t even last half that. The local independent Honda guy (OHV Motors in Eden Prairie) said that nobody seems to be able to rebuild them correctly, and after seeing the ?Parts Plus? drive shafts in his 180,000 mile ?88 Accord, admonished my friend to go only to the dealer or his shop for CV joint work.