Originally posted by: IGBT
MDMA also is related in its structure and effects to methamphetamine, which has been shown to cause degeneration of neurons containing the neurotransmitter dopamine. Damage to these neurons is the underlying cause of the motor disturbances seen in Parkinson's disease. Symptoms of this disease begin with lack of coordination and tremors and can eventually result in a form of paralysis.
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Related in its structure and effects doesn't say anything.
This is a common mistake made by well intentioned people, and a lot of people fall for it, but since I'm bored and the topic is something that I'm interested in and am quite knowledgeable about, I'll go ahead and educate you. I don't have a problem with you thinking ecstasy is a bad thing. It IS a dangerous drug - potentially fatal, and somewhat addictve. I
do have a problem with you using misinformation as the basis for your opinion, and spreading it around as fact when you haven't the slightest clue what the fvck you're talking about.
Methamphetamines are part of the molecule group called phenethylamines, along some hallucinogens like mescaline, 2CB and DOM, and enactogens like MDMA, MDA, MBDB, etc. Thats where the similarity in structure comes from. The similarities pretty much end there, unless you count that they both can come in pill or powder form.
MDMA is short for methylenedioxymethamphetamine. For some reason, people think because they can identify the last part of MDMA to mean 'methamphetamine', that means they automatically know what the drug does to the human body because, hey, it HAS to be related to methamphetmines right?
MDMA, and other 'enactogens' primarily affect serotonin. Methamphetamine affects dopamine. Methamphetamines have more in common with Cocaine than MDMA --- Cocaine also affects dopamine regulation.
The number one reason ecstasy kills people is because of the lack of an enzyme, cytochrome P450-246. 1 in 12 people lack the enzyme, which causes them to not metabolize MDMA or its variants correctly. In some people, this causes a fatal reaction that you may have heard referred to as malignant hyperthermia. Not everyone who lacks the enzyme will have this reaction. Most of the other short-term harmful effects aren't really that harmful if you take care of yourself by drinking the right amount of water (too much is bad, not enough is worse), not overexerting yourself, and having enough common sense to keep someone sober around to get you medical attention just in case something bad happens.
I'm not saying ecstasy is safe. I've done my fair share of it, I still do every once in a great while, and I do this knowing the risks involved. The most dangerous thing about ecstasy is that people start thinking they're invincible and do stupid sh!t like having unprotected sex with people they just met, mix other drugs with E, or pop a bunch of pills at once to 'get higher'. I think if you're going to rant about how dangerous ecstasy is you should focus more on stuff like that, instead of talking about long term effects that neither you or anyone else really understand quite yet.
and please, no more comparisons of E to Heroin? Heroin is seriously baaaaaad stuff. It will either kill you or turn you into a junkie. It was made for fvcking terminally ill cancer patients so they can at least die without pain, not for consumption by people who have an interest in living.