I know two people who were the type "I do this every day and it has never caused any problems." Both of them would hot plug in their keyboards, mice, and serial devices. Both of them ended up frying a motherboard eventually. One of them still does it.
From what I understand is the risk is greater when you do not plug it in straight and it makes a partial connection.
From what I understand is the risk is greater when you do not plug it in straight and it makes a partial connection.