Two things:
1.) Heat. One of my cards will not tollerate a temp of over 70c due to the overclock and stock cooling just wasn't enough. So if anyone currently owns an OC'd card and plan to add another be aware the added heat may compramise your oc. Bought an aftermarket cooler like I did with the oc'd card and the problem was resolved.
2.) I notice that in order to get the full SLI effects in some games you *must* enable " Disable Vertical Sync " in the nVidia game profile. Some games shut off VS, but some don't, even when you DO have it shut off within the in-game options.
Other than that its been awesome. Thought perhaps my X6 might hinder performance but for any title that counts I'm getting twice the performance and in most case's much much more. Not a single issue maxing out GPU usage either. Very cool upgrade for the money, nVidia/Ati have done a lot to make using two cards painless and anyone complaining about dual card issues just isn't manipulating the settings for each game correctly IMO. There's very little tweaking which is what impresses me the most.
Seemless install, incredible ease of use, it's pretty much plug and play. Definitely enjoying it.