I moved up here from La Habra, CA to Anchorage 2 1/2 years ago, and I'm enjoying it so far. I moved mainly to relax, slow down, and just get away from the hectic CA lifestyle.
Winters are kind of rough, but I can deal with it and I think I'm getting used to it. It's all about layering. I haven't wrecked driving in the snow yet so that's a feat in itself. The scenery is absolutely amazing. Lots of stuff to do if your the out-doorsy type. Skiing, snow-machining, camping, fishing, hiking, etc. etc...
I'm getting back into photography, love riding around on my mtn bike, summer bbbq's with friends, going down to Chair 5 in Girdwood for beer and pizza, Memorial Day weekends in Homer, going to Cheena (Sp?) hotsprings in the winter...
I guess the main thing you need to do if you decide to move up here, is get out, meet and make a good group of friends, and explore

I don't regret it, and I plan to stay up here a while. Anchorage is a big enough town where you don't feel totally out of touch with the lower 48. The cost of living isn't much more than living in southern california. I don't miss traffic, but I guess the biggest gripe I have is the variety of restaurants and food I'm used to from back home.