According to the "Intarwebs", Dexter killed about 70+ people... far more than the 29ish Lecter. Dexter would win IMO, but Lecter is much more outwardly sadistic.
"Punleu wroteon August 24, 2009 at 7:39pm
Alright, I've watched the series over and this is what I've gotten.
Dexter killed 11 in Season 1 and 9 in Seasons 2 & 3. (Including flashbacks)
End of Season 1
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46 Slides + 2 (Nurse, Brian Moser).
They didn't show Dexter taking a trophy with the nurse and he purposely didn't take a sample from Brian.
>48 confirmed kills.
Between Seasons - 38 Days. 0 Kills, Doakes stalking.
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>48 confirmed kills
End of Season 2
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>57 confirmed kills
Between Seasons - 27 days, 5 kills
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>62 confirmed kills
End of Season 3
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>70 confirmed kills (including Camilla)
So Dexter has 70 confirmed kills, although his estimated kill count (EKC) could be as high as 80, give or take. I'm going to guess he didn't start taking slides right away. He studied blood in college so its likely he may have started there. So between his start and that opportunity, and without police aid, I'm estimating 10 kills.
Confirmed kills for his victims is about 117. Estimated kill count could be as high as 400. The Nurse, Coyotes, Brian, Little Chino, and Skinner have 30 combined confirmed kills but have likely killed hundreds more.
It is also possible to assign Dexter multiple assists.
But all in all, by killing 80, Dexter has avenged about 400 kills and prevented many more."