From a previous article : 
The Envelope 
Stand-up comic 
Greg Giraldo was hospitalized for an accidental overdose of prescription drugs Saturday night, the New York Post 
reports.
 A Comedy Central regular and 
judge  on "Last Comic Standing," 
Giraldo was found unresponsive during a party  in his New Jersey hotel room after performing at the Stress Factory in  New Brunswick, N.J.
 The 44-year-old comic, initially in critical condition according to the Post's source, was breathing on his own by Sunday.
  	 	 	 	 	 In addition to his four nights at the club, the 
recovering alcoholic had been booked  to appear Saturday afternoon at 
the New York Recovery Rally, billed as an event to "celebrate recovery from addiction."
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A recovering alco would be at risk for this type of stuff.  Do we know what kind of drugs he overdosed on?
RIP