I have the original Graphire, which I use occasionally for graphics and Flash. I also own a Logitech Wireless Optical Mouse. When my Logitech dies in the middle of a game, I use the Graphire mouse until I can swap the batteries in the Logitech.
The only real disadvantage to using the Graphire mouse is you have a very limited mousing space for what is an unnecessarily large mouse. The Graphire2 has the same problem (large mouse, small pad). Unlike other wireless mice, you MUST use the Graphire mouse on it's own pad (which is wired), since the Graphire mouse is really nothing more than an unpowered transducer.
On the other hand, my Logitech can be used on my pants, if I really wanted to.
