Appalachian Trail. You could do a drive on skyline drive/blue ridge parkway first. Keep in mind i don't do a lot of hiking.
http://www.nps.gov/shen/planyourvisit/hiking.htm
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I really enjoy climbing volcanoes. I've done Mt Baker, Mt Adams, and Mt Garibaldi so far. I'm aiming to do Shasta and Rainier next. Baker is somewhat technical (you need to rope up etc), but Adams isn't. It's a long slog up a hill, but the view is epic.
Isle Royale is on my list as well.
I think it will be Glacier -> Isle Royale
Me too ... and we are planning on bringing our two huskies, as they love to hike with us 🙂.
We definitely don't mind hiking 15-20 miles a day wit a day pack, and 10-15 with our actual packs.
http://www.youtube.com/watch?v=ejVbZyCE99U&feature=youtu.be
Minnesota has some hills..
From last weeks hike. Sorry if the music annoys you 🙂