I've played through 2 levels of it so far and I am really loving it. I am using the wiimote/nunchuck control scheme (I see it as a strength for FPS's on the Wii). I had to do some tweaking and some questions on various forums. But this is the best I've seen:
Go to the Wii's controller settings on the GoldenEye menu, and click Customize.
Go into cursor settings and do the following;
1.Set the deadzone to 15 above, 35 across.
2.Set the maximum turn to 100 (which is default)
3.Set the horizontal speed to 30
4.Set the verticle speed to 9
5.Set the cursor sensitivity to MAXIMUM.
Now go into the ADS options, and do the following;
1.Set the deadzone to 17 above, 17 across.
2.Set the maximum turn to 90 above, 90 across.
3.Set the horizontal speed to 20
4.Set the verticle speed to 10
5.Set the cursor sensitivity to MAXIMUM.
Now exit those options, and set the camera to; Wii Remote Turning, and turn 'Look' OFF. Have the Auto re-centre and Turn while cursor off-screen settings ON