QFT. Especially with air cooling. Thinking about what the motherboard absolutely needs connected to it and knowing how to get rid of slack can help keep things clean and maintain optimal air flow.Just some planning ahead, routing wires the same way, and trying to find ways to hide them. Going behind the mobo tray is a common area to hide the wires.
The wires that you see connected to my motherboard tray here are ALL of the wires that you can actually see looking inside of my case. Everything else is either routed in the front throught the drive-bay areas, underneath by the hard drive cages, or around the back of the motherboard tray.
Needless to say, a dongle isn't an issue with internal wiring at all.