Call your hotel, see if they offer free parking. If they don't, fly. You can take the
BART (Bay Area Rapid Transit) from the airport into the city, if you don't want to spring for a taxi. Check their routes, and you'll see the yellow line goes right into and out of the airport.
So far as the drive goes, I drove from Castro Valley (about 25-30 miles outside of SF) to San Diego (32d Street Naval Station), back in 87. 485 miles, one way. The national speed limit was still 55 back then, but once you hit the 5, you were a slow poke if you were doing less than 80. Just keep an eye on the truckers, as they're talking to each other on their CB's, and will slow down in plenty of time for the occasional speed trap. When they slow down, you do....when they speed back up again, you do too.
The only thing that can possibly slow you down then would be a bad accident (with all the looky-loos), or fog (can get pretty thick in the central valley).
Oh yeah, and I did that drive in 7 hours, with no stops, and slowing down to 65 once I hit L.A. (I was getting sleepy by then). If I'd stuck with the truckers, I probably would have made it half an hour faster. :whiste: