A couple of other bugs I noticed.
Invisible enemies.
I'm not sure where or how this happens all the time, but I know one of the first places this happens consistently is in the opening Vault 101 sequence. When you are making your way to the Overseer's office and move up the broken door to the top floor, a bunch of radroaches are suppose to spawn. Sometimes they all do, but usually a few of them do not. You can clear out the area, but you'll still get the constant insect clicking sound and a red bar on the compass indicating an enemy nearby. The invisible or stuck roaches can't hit you or effect you in any way, but they are annoying. You CAN get them to pop back up, but only by zoning out and back in. When I do that, they appear again.
I also know that certain piles of "debris" don't do collision detecting for everything. If yuo walk over it, you walk over with correct collision detection, and if something else goes there, they use the floor below for collision. To prove this I know one spot that is great for this. In Rivet City at the market place on the boat there are a ton of items on the shelves. Of course if you steal those items while they are on the shelves, everyone will see you. However, you can use the Z key to pick up an item and MOVE IT without actually being considered for stealing an item. I usually do this to steal stuff from any shop with items on the shelves. I just use the Z key and drag off to some corner where no NPCs are looking and then actually use the E key to steal the item. Works all the time.
Well, with that in mind, in Rivet city, behind the weapon dealer, is a little corner in the shadows. There is a couple of barrels and a pile of trash debris. If you drag an item over that trash and drop it, the item drops through the debris pile to the floor beneath and can no longer be reached. If you walk over the trash, then you collide with the trash pile and walk up on the trash. Items will slide right through it to the floor below.
I know this happens in the weirdest places for both items and baddies. In the Marigold subway station, I've ran across random giant fire ants under trash and fallen debris. I can see them on my compass, hear them, and sometimes even see an antenea stick up and move around from under the pile, but in no way can I target or interact with the ant. Nor can they with me.
Another strange bug I've found deals with collision detection when using VATS. Sometimes I get a critical hit with a 1 shot 1 kill hit on a target, but instead of blowing whatever body part to bits I shot, the whole bad guy goes flying out of control. I mean like being shoot backwards in a flip or shooting up straight into the air about 40 or 50 feet before coming back down. It is really odd and funny when that happens.
I've also seen bugs dealing with criticals that cause damaged parts to blow up but they don't go anywhere. Take a humanoid raider for example. If you do a critical headshot for a kill sometimes the whole had will blow up in a gorey explosion. Parts of the skull, eyes, brain, and what not go flying all around. This is what usually happens. On a few occasions, I get that critical, but the exploded body parts go no where. Meaning they are on the neck stump, the head is not longer recognizable as a head, but the gore parts are still held in thin air next to the bloody stump of a neck. Kind of odd.
The last bug I've noticed is related to this. No matter what the body part, or how far it has flown, you can loot everything off whatever you killed from that one piece. Every time it happens I think, "Oh look, I just found this assault rifle in this eyeball here!" Then I imagine myself pulling up that rifle out of an eyeball. Guess it is extra dimensional or something.
Last bug, and it's minor, relates to Ronald Lauren in Girdershade. If you enter his house first while he's not there and haven't talked to his wanna be girlfriend first, you will lock up in his house. I think the game is trying to do a script with him, but since he's not there ,and won't show up there until you get the quest to gather nuka cola quantum, the game bugs out.
I found a few more, but they are really minor. The ones I'm finding are inherent bugs in the game. They aren't driver or hardware related and would be on platform and PC. The autosave lockup bug is the most annoying one.