Write behind caching basically means data that is sent to be written to your drive media won't get written immediately. Instead, it will be written first to a cache memory(presumably system memory), and then later on be written in larger chunks to the drive media. The idea is that this will be faster and more efficient since you won't be writing small chunks of data to the slow drive media all the time.
However, in sensitive operations like streaming media and CD burning, its safer to disable write behind caching because if you do multiple disk accesses at the same time, data might intefere with one another and there's no gaurantee that data that is supposed to be written will in fact be written. Also, in the case of a power outage, you will risk losing some data.
Since you mention the checkbox in the removable disk tab...it shouldn't matter to your SCSI HDD, unless you somehow have an external SCSI HDD, or have checked the "removable" box in your HDD properties. OTOH, in the "Troubleshooting" tab in file system properties, there is also a checkbox marked "Disable write-behind caching for all drives", which affects all drives, removable or not. If you're usually multitasking with sensitive data and operations, you might want to check that box for added safety. For all other uses, it should be fine to leave it unchecked for that extra speed.