With the NF4 chipset, I think you can use the nVRAID app to actually RAID partitions, and not just drives. That way you could split each of your drives up into two partitions, one for data and one for your apps and OS. You could go RAID 0 on the apps and OS partition to get better performance, while running the data partition at level 1 for data security.
And lansalot, I agree with you about the CPU usage thing. With the huge processing power available nowadays (and with mutlicore inevitably taking over the desktop), you really don't need to sweat CPU overhead like you used to. Also, if you are using a software app like DiskSuite, Veritas Volume Manager or even the lowly Windows Dynamic Disks you don't have to worry about being your array being tied to a single type of controller. If you have a massive hardware failure and you are relying on the RAID controller's BIOS to manage the array, you probably won't be able to get the array back up and running if you are forced to plug the drives into a machine with a different controller in an emergency. Using software RAID also tends to make upgrading your system later a lot easier as well