Here's the update so far.
The crashing/restarting due to opening up multiple files/programs was due to a microsoft security/hotfix/patch since SP2, that wasn't installed.
I was reluctant to do so, but in a last ditched effort, and per advice of cmdrdredd and n7, I raised my vNB to 1.55V from 1.44V. My FSB is at 1.4V, SB is at 1.6V, vcore in BIOS is 1.45V, and vDIMM is 2.1V (firestix's rated voltage).
for DDR2-945 (4:5, 378x9):
At 1.45V vNB, I was only stable for 2-2.25hr with orthos blend (16+hrs stable with orthos small fft). However, at 1.55V vNB, I was stable for orthos blend 8.75 hours (16+ hrs stable with orthos small fft). Since I'm going to be using this system mainly for video conversion/editing/encoding, I would like to have it orthos blend stable for 16-24 hours, but then again, I'm not sure if encoding a movie would be as "stressful" on my components as running orthos blend.
So at this point, is it more likely my RAM or my motherboard? I initially thought RAM, but I'm beginning to think it's my motherboard (perhaps even both?). Unfortunately I don't have another system that accepts DDR2, so I can't test the sticks out that way. The sticks didn't fail memtest @ DDR2-945 for 7 passes (~8hrs?).
Any one have any suggestions at this point?
Thanks again, everyone.