IMHO- YES!
VERY much.
For the average person, satisfied with 1024x768, or not overly demanding then almost any modern graphics card is perfectly suitable. In fact many enthusiasts are reasonably happy with almost any modern card as high as 1600x1200 from what I've seen.
If you consider yourself to have reasonably good eyesight or are particularly discerning when it comes to image quality, you'll likely find a noticeable difference between poor and good cards. If your doing any sort of 2D graphics design or working in resolutions above 1600x1200 then you owe it to yourself to get the best you can afford.
My roundup:
nVidia:
TNT1/2: Horrible, 1024x768 max IMHO. A few manufacturers were slightly better then the norm, but by and large the 2D quality was terrible.
GF1/2 A definite improvement but still leaves a lot to be desired, most should be satisfied but the more discerning won't be too pleased. Most brands I wouldnt go above 1280x1024, Elsa, LeadTek, Gainward, VisionTek are borderline for 1600x1200.
GF3: An incremental improvement, but overall the status hasnt changed much.
GF4: Another mild improvement, but 2D still varies between manufacturers. The better manufacturers are finally passable at 1600x1200 but nothing particularly impressive.
LeadTek GF3 Ti500: I put this in a cetegory of it's own b/c for some as yet unknown reason, LeadTek's Ti500 seems to consistently bare remarkably good 2D quality-better then I've seen from any other nVidia based board and pretty decent at 1600x1200, though not above.
ATi:
Rage 128/128Pro/Dual Rage 128Pro: Decent enough, borderline to passable at 1600x1200... maybe a notch below the better GF4's.
Radeon VE/7000: Similar to the Rage 128 boards but more consistent.
Radeon/RadeonLE/Radeon 7200-7500: Pretty good at 1600x1200, no real complaints. Their not great but their solid with no definite weaknesses. As with most anything else, they fall apart very quickly once resolutions reach above 1600x1200. A few of the better R7500's seem a notch above the rest.
Radeon 8500/8500LE: For all intents and purposes my opinion is essentially the same as with the R7200-7500.
Radeon9700: Only seen a few on average 17/19" monitors, so I don't think I've seen a wide enough variety on a selection of quality monitors to make a judgement. I've heard their slightly better then R8500's though, but cannot confirm.
3dfx:
Voodoo Rush: TERRIBLE! They make the TNT1/2 look fantastic. Even 800x600 is only average really... perhaps the worst 2D quality I have viewed in any graphics card manufactured post 1995. Grab a cheap S3/Trident 1MB board and your better off for 2D quality.
Voodoo Banshee: Not much variance between manufacturers and surprisingly good 2D. Average quality at 1600x1200, not viable at all for anything higher.
Voodoo3 2000: Similar to the Banshee, except there is virtually no variance between different boards.
Voodoo3 3000/3500TV: Remarkably good for the time and still quite solid. Excellent quality at 1600x1200, barely passable at anything higher...though even 'barely passable' is still better then virtually anything else.
Voodoo4/5: Actually a slight step back from the V3 3000/3500 IMHO, average to good quality at 1600x1200. Again, not viable at all for any higher,
Matrox:
G200: The king of the day, and still solid. Average quality at 1600x1200, though the max refrsh rate supported is a bit low.
G400/450/550: Fantastic quality. Virtually perfect at 1600x1200, and passable at 1920x1440....I wouldnt use it regularly at 1920x1440, but it's decent enough for short stints. As good as if not better then anything I've seen from 3dfx/ATi/nVidia. Strangely enough, some G550's seems a little inconsistent and their not always quite as good one would expect of Matrox.
Parhelia: The reigning king, and a hefty improvement over what was already extremely good in the G400/450/550. Virtually perfect and 100% crystal clear with stunning color definition even at 1920x1440. 2048x1536 is definitely excellent though not perfect.
Raises the bar for what I previously considered 'perfect', even as low as 1024x768 it manages to somehow look crisper then I've seen from any other graphics card.
The only real card to consider for the Pro2D artist, though hardly anyone else will really benefit from the stellar 2D it offers.
A few quick comments: Most Pro3D rendering cards arent quite as good as one might expect for 2D design, though by no means bad.
Appian consistently manages to get slightly better 2D quality from their boards then do the original chip manufacturers.
The Matrox MMS series seems to offer a bit better quality then do their dirivatives their based off of.