They used to be more picky - I have an Asus K7M (AMD 750 chipset, for SlotA Athlons - not the current stuff!) and I could not make it take the Kingston ValueRAM i had bought. But let me emphazise that this is not valid with the current stuff...but with the KT133A chipset motherboards, the best OC results come from overclocking the FSB (not the multipler, as was the case with the KT133) and to overclock the FSB you need high quality RAM. Generic should work fine at its default speed, however, but don't expect to get any good OC results