The problem is that the expression "chemical imbalance" is bandied around so much that you'd think everyone and their dog needs to be on strong medication just to be able to be alive. It's a wonder that the human race got this far without dying off from mass suicide brought about by worldwide depression.
I don't think there can be any question that pharmaceutical companies are guilty of "pushing" for wider use of their medications to encompass a broader range of symptoms and maladies than the particular groups on which their medications were originally tested/developed for therapeutic efficacy and approved for use.
But to go radically further and deny the disorder ever existed in the first place and to imply it was merely the 'invention' of the pharmaceutical industry is not only raw stupidity, it can contribute to a dangerous climate of ignorance where a person who needs help will not seek it because the 'conventional wisdom' they've been exposed to is that these disorders are not "real", they are nothing more than a fancy name for one's personal failings and character flaws.
I suffered with narcolepsy for some 10 years, believing I was at fault because I couldn't stay awake in the daytime, sleep at night, wake up in the morning, and was fatigued all the time. Thanks to idiots like EngineNr9, I bought-in to the belief that disorders such as "chronic fatigue syndrome" was just a medical name for someone who was lazy or maladjusted. That if you couldn't stay awake or were always tired, it was some how your own doing, that you could control it, but chose not to because of some character flaw or life-style choice.
So I spent years in a viscous cycle of futility, trying to 'heal' myself, thinking that if I just tried a little harder I could get a handle on it, after all, this was a personality flaw not a medical condition. It cost me two car accidents from falling asleep at the wheel, dozens upon dozens of near accidents, two jobs, some major debt I'll never recovery from unless I file for bankruptcy, not to speak of social problems which resulted from the inability to stay awake long enough to relate to anyone. Its nice when you nod off on your girlfriend as you're having sex, that makes her feel VERY special.
It's nothing short of a miracle I didn't kill anyone or myself in the two car accidents and the numerous near-accidents I had. Waking up in the opposing lane of traffic was a weekly occurance for many months. I often resorted to pain as a means to keep myself awake, use your imagination. It didn't last long, but it usually lasted long enough to keep me awake the extra 5 or 10 minutes that I needed to get home.
Narcolepsy is caused by the oft-maligned "
chemical imbalance". A deficit, in fact, of a group of neuropeptides (neurotransmitters) called hypocretins or orexins that are directly implicated in sleep and wakefulness, among other functions associated with the hypothalamus. But, EngineNr9 would probably say I'm just bored or lazy and need to join the military for some discipline, that will magically reverse the damaged area of the hypothalamus responsible for producing the hypocretins.
If anyone bothered to read the alleged 'support' for EngineNr9's assertions that depression is a pharmaceutical industry 'lie', a New York Metro article entitled 'Inside the Happy Business', not one statement appears within that article that can be construed as support for his argument. At no point does the article or anyone quoted within it challenge the validity of severe depression nor the need for neurobio drugs to treat it.
Further, the pharmaceutical industry is not solely responsible for the gradual loosening of diagnosing and prescribing standards. Physicians want to help their patients. What do you think a physician is going to do when he has a patient who is clearly at the end of his/her rope and needs help but doesn't precisely fall within the most rigid and conservative definitions and guidelines for clinical intervention, say "Sorry chum, but I can't help you...have a nice day"?