It has been much discussed, and I've gotta wonder about the people that have c: partitions of 10+ gigs & W9x. Either they don't have much on these partitions, don't defrag, or don't care how long the defrag takes. Yes, I could start a speed disk before I go to bed, but, I prefer to just do it and have it take ~3 minutes.
I prefer to have LOTS of partitions. (2) 27 gig WD's with partitions through M: If you are easily confused, you can always label the partitions.
I put all of what I consider essential stuff on my C: partition. O/S, utilities, apps and utilities that I use almost daily. This way, I can image and defrag just a single partition, frequently.
Then for most people, partitions such as:
apps
games1
games2
store1
store2
--Randy