I've got both the DFI and the A8N-E.......my view, if you're going non-SLI, the Asus is the way to go. BUT, if you need firewire, you'll need to go DFI or buy a card which is dumb. I have Firewire through my Audigy Plat. so it wasn't a factor, but, something to think about. I love the Asus board, very stable and very easy, straightforward O/C'ing. I can actually get higher with the Asus now than with my DFI, but I attribute that to better ram with the Asus.
You won't be disappointed with either, but, I have to like Asus for easy RMA and support if needed, where I've heard from several people about dsmal support and horrid RMA expiereinces with DFI.
Get the one YOU want and have fun with it!🙂