For that large of room and the watts are low, I suggest speakers from PSB or Klipsch because of their efficiency. The subwoofer is going to be a problem because for that size, a DIY subwoofer is the best, but this can be a problem if you are new at this. I suggest subwoofers from Outlaw and Elemental Designs. For that size of room, I recommend two Outlaw The LFM-1 EX or two Elemental Designs A5-350.
Sure you could go for Infinity or Polk, but you actually paying for the technology that is put into their products instead of the actual speaker. When going for PSB and Klipsch, you are paying for the actual speaker. BOSE is the worst of all the brands because you are paying for the technology and not the actual speaker. I feel the PSB and Klipsch is reasonably price for their quality. If you are selecting PSB speakers, I suggest their Image series.
To know how much the actual wattage output for each channel for an AV receiver or any amplifier, look at the back of the unit where the AC is coming in. Some state the VA and others state the voltage and the current. The VA is what you want, but you have to use the voltage and current if it is not stated. To get the wattage for the amplifiers in AV receiver, take what the watts are consume and minus about 120 watts. This is just for the electronics or the processing. 120 watts is for powerful processors and about 60 watts for low power processors. Next take the number and divide by the amount of channels going to be used. Finally multiply them by 75 percent. Usually AV receivers uses Class-AB and they are roughly 75% efficient.
Do not forget to break the speakers in because new speakers will sound like crap. It may take up to two to four weeks to break them in. Good speakers will show them selves after the break-in period while crap speakers will just be bad.
If you are going for on-line buys, buy from an authorized dealer. I recommend Crutchfield.com because they are helpful for novices and they are an authorized dealer.
I suggest audio and speaker cable from Dayton Audio. They have the same performance as Monster Cable, but at a fraction of the price.
Do not use different metals for connecting cables because that is worst than having oxidation.
I suggest a DLP TV from Mitsubishi. DLP TV are better than LCD and better than plasmas.