CAR-T therapy forces autoimmune diseases into remission

JTsyo

Lifer
Nov 18, 2007
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Engineered immune cells, most commonly used to treat cancers, show their power against lupus and other immune disorders.

If this is a general cure for auto-immune conditions, it'll be huge. Just working against the 3 mentioned in the article is great.
 

hal2kilo

Lifer
Feb 24, 2009
26,023
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If this is a general cure for auto-immune conditions, it'll be huge. Just working against the 3 mentioned in the article is great.
Next, stem cells tech that regenerates your worn out cartilage. Damn, ads for doctors in the Seattle area advertising this, but I don't know if it's FDA approved. If it Fn works, me and millions of people will be lining up for this treatment if it doesn't require having a second mortgage on your home. I really don't want to replace my knee or hip joint but the way things are going, it may be in the cards and that is some serious surgery and rehab.
 

mikeymikec

Lifer
May 19, 2011
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Awesome. Selfishly interested because I have Crohn's disease (not much in daily symptoms and issues, thankfully). I would like to stop having to take horrendously expensive medication though!

<waves at fellow Crohn's club member>

Mine is being kept in check with diet and mesalazine, pretty moderate compared to some people, but still, it would be life-changing to suddenly not have it any more after just over twenty years.
 
Dec 10, 2005
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Next, stem cells tech that regenerates your worn out cartilage. Damn, ads for doctors in the Seattle area advertising this, but I don't know if it's FDA approved. If it Fn works, me and millions of people will be lining up for this treatment if it doesn't require having a second mortgage on your home. I really don't want to replace my knee or hip joint but the way things are going, it may be in the cards and that is some serious surgery and rehab.
No, those things are not FDA approved and operate in a poorly regulated space that takes advantage of people and puts patients in potential harm's way.
 
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hal2kilo

Lifer
Feb 24, 2009
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No, those things are not FDA approved and operate in a poorly regulated space that takes advantage of people and puts patients in potential harm's way.
That is kind of what I figured, but they have ads on the radio every Fn day about their wonderful stem cell solutions. With supposed people who swear that fixed them.
 
Dec 10, 2005
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That is kind of what I figured, but they have ads on the radio every Fn day about their wonderful stem cell solutions. With supposed people who swear that fixed them.
Like I said, under-regulated space that charlatans are using to make a quick buck, at the expense of patient safety and trust.

A few years ago, there was an article talking about some of these stem cells clinics in regards to vision loss, and in some cases, people lost vision or were otherwise materially harmed by these unregulated and unproven procedures.
 

hal2kilo

Lifer
Feb 24, 2009
26,023
12,266
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Like I said, under-regulated space that charlatans are using to make a quick buck, at the expense of patient safety and trust.

A few years ago, there was an article talking about some of these stem cells clinics in regards to vision loss, and in some cases, people lost vision or were otherwise materially harmed by these unregulated and unproven procedures.
I should know better. The FDA became a joke when they let the herbalist have their way with no empirical data.
 
Dec 10, 2005
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Same difference.
I don't think it makes the FDA a joke. Just that they can't reliably intercede on non-medicines thanks to laws Republicans championed. We should be putting the blame on the correct spots instead of throwing up our hands and blaming the system as a whole.
 

[DHT]Osiris

Lifer
Dec 15, 2015
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I don't think it makes the FDA a joke. Just that they can't reliably intercede on non-medicines thanks to laws Republicans championed. We should be putting the blame on the correct spots instead of throwing up our hands and blaming the system as a whole.
Might require more information than is reasonable for the layman. If the purpose of these agencies is to serve the people in a way that frees them up to do their thing, how does it help to have homeopathic shit on the shelf next to the eye drops? If I've gotta search for the 'snake oil' label on every box, hypothetical layman me might start asking what an FDA is even doing.

Now I understand their role, but not everyone does.
 
Dec 10, 2005
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Might require more information than is reasonable for the layman. If the purpose of these agencies is to serve the people in a way that frees them up to do their thing, how does it help to have homeopathic shit on the shelf next to the eye drops? If I've gotta search for the 'snake oil' label on every box, hypothetical layman me might start asking what an FDA is even doing.

Now I understand their role, but not everyone does.
Yes, I think the FDA should be able to regulate those things, instead of those products just having labels like "The FDA has not evaluated this product's claims".
 

Pens1566

Lifer
Oct 11, 2005
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Good news on the results.

However, the means are still pretty horrendous. As the article points out, CAR-t is a nasty process. Typically a last resort where others have failed. And they're still not sure if it was the CAR-t or the massive induction chemo.

But a good step in the right direction overall.