OHC is more efficient. Friction, weight, strength.
Friction in that the aren't all the extra parts involved with OHV.
Weight, for the same reason, since it takes HP to move that extra weight.
Strength since by eliminating the pushrod, you eliminate a major weak link. Pushrods also flex a lot, which causes loss of valve lift/duration. Not really that critical except in racing applications, but it does happen.