In theory you can run more than 1 video cards simultaneously (I run a triple monitor setup with three cards) but games will normally f_ck up when running other Apps at samte time. When I play a game I do not try running other Apps at same time but I do not disable my other cards either.
You can run two Voodoo2s in SLI mode, and you can use one AGP card and one PCI card to run two monitors, so there are instances in which you can use two video cards at the same time.
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