yep. i did that once on my Asus T100
however, you might have to find/install the drivers manually (from dell's website). I don't remember the OS automatically activated or not... back then (end of oct during launch), asus's website was missing the drivers, so I didn't play around much, ended up restoring the default OS
there wasn't much bloatware on my T100 anyways... just the asus utilities, auto-update and netflix icon in metro